In powder form, the dietary aid is red-brown in color; its shade is … There are conflicting studies on use of lycopene for cardiovascular disease. Scientific literature documents lycopene’s antioxidant activity and its use in cancer prevention (breast and prostate), as well as its use in the prevention of cardiovascular disease. Doses ranged from 4.5 to 15 mg/day (mean, 12.4 mg/day) for a duration of 4 to 16 weeks (mean, 8.3 weeks); average net change in SBP ranged from −11.5 to 2.4 mm Hg with an overall pooled estimate of −4.95 mm Hg. Reductions were most significant in Asian studies, for those with an initially higher baseline SBP (greater than 120 mm Hg), and with higher dosages (> 12 mg/day).103 Similar results were found from a meta-analysis of 4 intervention trials published between 1955 and 2010.109, The effects of oral lycopene supplementation on vascular function was investigated in a randomized, double-blind, placebo-controlled trial with parallel arms including statin-treated patients with cardiovascular disease (CVD; n = 36) as well as healthy volunteers (n = 36). There are several published studies that evaluate whether lycopene in tomato products or supplements could have protective effects against prostate cancer and cardiovascular disease. No toxic effects were observed in rats treated with lycopene 2,000 mg/kg/day for 28 days, an intake similar to approximately lycopene 200 mg/kg of body weight per day in humans.86 Another 13-week toxicity study generated similar results. However, lycopene is POSSIBLY … Lycopene is primarily available in capsule and softgel form, with dosage guidelines from manufacturers ranging from 10 to 30 mg taken twice daily with meals. Fat also enhances the absorption of lycopene. Protect your prostate against free-radical damage with the antioxidant power of Swanson + Vitamin B1 2 mg + Vitamin D3 200 IU + Vitamin B6 1.5 mg + Vitamin B12 1 mcg + Vitamin E 10 IU + Vitamin C 50 mg + Niacinamide 20 mg + Calcium pantothenate 5 mg + Folic Acid 0.3 mg + Ferrous Fumarate 90 mg + Copper 0.5 mg + B Carotene 10% 4.77 + Ginseng 45 mg + Lutein 8% 3 mg + Potassium Sulphate 2 mg We comply with the HONcode standard for trustworthy health information -. This is because lycopene might slow blood clotting. Get the best deals on Lycopene Capsule Vitamins & Minerals and stay healthy at home while you shop our large selection & lowest prices at eBay. This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. 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Lycopene suppressed tissue factor activation in vascular thrombosis in human endothelial cells.41 Additional studies found that lycopene reduced expression of cell surface adhesion molecules and binding of monocytes.42, 43 Lycopene also bound and inhibited platelet-derived growth factor, which is associated with the development and progression of cardiovascular disease in rat smooth muscle cells.44 One nutritional study in rabbits compared lycopene's action in reducing the formation of atherosclerotic plaques in the aorta with that of fluvastatin.45 There are studies on the development of more efficient vehicles to deliver lycopene to adipocytes.46, In 19 subjects, lycopene supplementation decreased serum lipid peroxidation and low-density lipoprotein (LDL) oxidation, suggesting a decreased risk for coronary heart disease.47 An epidemiological study in 10 European countries confirmed beneficial effects on the heart correlating with lycopene lipid levels and reduced risk of myocardial infarction.48 The Austrian Stroke Prevention Study found that certain concentrations of lycopene and other antioxidants may protect against cognitive impairment.49 Plasma LDL cholesterol concentrations were reduced by 14% in 6 men consuming dietary supplements of lycopene 60 mg/day for a 3-month period.50 In a 6-week clinical trial, 24 patients receiving fresh tomato and tomato juice twice daily reported reduced triglyceride levels and LDL cholesterol and increased high-density lipoprotein (HDL) cholesterol.51 In studies conducted in overweight individuals, both dietary and supplemental lycopene led to an increase in HDL cholesterol levels52 and a reduction in HDL-associated inflammation.53 In another study, low lycopene concentrations were associated with carotid atherosclerosis in 220 asymptomatic individuals.54, When the effects of tomato extract supplementation were studied in 50 moderately hypertensive individuals, supplementation for 6 weeks was associated with reduced systolic and diastolic blood pressure (SBP and DBP, respectively) and increased serum lycopene levels.55 A meta-analysis of 6 blinded intervention studies (N = 494) evaluating the effects of lycopene or lycopene-containing products on blood pressure found that lycopene supplement decreased SBP significantly (P = 0.012) but not DBP. Based on the results of 5 relevant studies with no substantial heterogeneity, lycopene showed no significant association with cataract risk.101, Lycopene may be effective as a first-line therapy in treating oral submucous fibrosis56 and in combination with other therapies in treating gingivitis.57 A randomized, double-blind, placebo-controlled trial (n = 50) found no difference between groups treated with lycopene-enriched olive oil or placebo (water) for treatment of burning mouth syndrome or its symptoms.104, Reports of positive outcomes with beta-carotene in skin disorders including cancer, pigment imbalance, and photodermatoses, are available,58, 59, 60, 61 but lycopene may not share these effects because of its structural configuration. Triple Strength Lycopene are 3 x Strength of Regular Tablets. turmeric, saw palmetto, Ginkgo Biloba, garlic, echinacea. Medically reviewed by Drugs.com. Lutein Only 1 study reported incidence of prostate cancer (10% vs 30% in the lycopene vs control groups).29 Another review of 8 randomized controlled trials found study quality varied significantly, making conclusions impossible.30 Lycopene also inhibited the progression of benign prostate hyperplasia.33 Lycopene concentrations changed rapidly in men with prostate cancer given lycopene supplements for several weeks prior to radical prostatectomy. Lycopene 6% 2500 mcg + Vitamin A 2500 I.U. Using a 3rd Party Independent Lab guarantees that the results are objective and unbiased. Prime members enjoy FREE Delivery and exclusive access to music, movies, TV shows, original audio series, and Kindle books. In general, tomato-based products and lycopene supplements are well tolerated. One trial reported a cancer-related hemorrhage in a patient taking lycopene, but causality was unclear. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Special Precautions & Warnings: Pregnancy and breast-feeding: Lycopene is LIKELY SAFE during pregnancy and breast-feeding when taken in amounts commonly found in foods. Get info of suppliers, manufacturers, exporters, traders of Lycopene Capsule for buying in India. 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Other sources include apricots, cranberries, grapes, pink grapefruits, guavas, papayas, peaches, and watermelons.2, In North America, nearly 85% of dietary lycopene is derived from tomatoes and tomato-based products.1 Tomatoes have been cultivated since the 16th century as a food source. Abundant in tomatoes especially, but also […] Lycopene is LIKELY SAFE when taken by mouth in appropriate amounts. Bottom Line Lycopene is a plant nutrient with antioxidant properties. Lycogard Capsule is used for Vitamin a deficiency, Leg pain due to blocked arteries, Skin diseases, Skin infection, High blood pressure, For eye and ear wash, Uterine cancer, Red blood cell production, Eye problems, Wound healing and other conditions. Although numerous animal studies exist,4 only clinical evidence was reviewed in the following studies. Some GI complaints (eg, diarrhea, dyspepsia, gas, nausea, vomiting) are documented. THE BASICS OF LYCOPENE Lycopene (pronounced LIE-co-peen) is a nutrient in the carotenoid family (where you can find lutein , zeaxanthin and many others) that’s naturally found in some plants. Lycopene is lipophilic and insoluble in water. Apoptotic activity was observed and may have been caused by lycopene.34 Prostate volume was reduced in prostate cancer patients taking 30 mg/day of lycopene extract for 3 weeks prior to radical prostatectomy.34 In 997 middle-aged men, an inverse association was found between serum lycopene levels and overall cancer incidence. Lycopene 20mg Per Serving - 200 Capsules - Lycopene Supplement - Super Antioxidant which Helps Support Immune System and Prostate Health 4.4 out of 5 stars 309 $19.99$19.99 ($0.10/Count) Get it as soon as Tue, Dec 15 Manufacturer of Capsules - Prebiotic & Probiotic, 100 % Lycopene With Multi Vitamin, Calcium Carbonate 200mg Alphacalcidol 0.25mcg and Silymarin B-Complex … Lycopene extract is usually low in cost and readily available in most health food stores. The various lycopene benefits such as being a cancer fighter and antioxidant, are what put this substance on the map, not its color. Avoid with hypersensitivity to lycopene or to any of its food sources, especially tomatoes. Lycopene is responsible for the bright red color in certain foods such as tomatoes. SKU: LY3, Swanson Super-Strength LYC-O-Mato Lycopene 40 Milligrams 60 Sgels, Oregon's Wild Harvest Prostate Health with Lycopene Capsules, 60 Count, Healthy Origins LYC-O-Mato Lycopene 15 Mg, 60 Softgels, Spring Valley Lycopene 10 mg, Prostate Health, 60 Softgels (Pack of 2), 21st Century Lycopene 25 mg Tablets, 60 Count (22400), Solaray Lycopene, Softgel (Btl-Plastic) 10mg | 60ct, 21st Century Lycopene 25 Mg Tablets, 60-Count (Pack of 3), Lycopene 30 mg All Natural Prostate Supplements for Men. Check price at AmazonNOW Lycopene keeps it basic, but this formulation has a solid dosage of 20 mg of lycopene per capsule, which is delivered in rice bran oil and a gelatin capsule. Clinical studies evaluating the benefits of supplemental lycopene in pre-eclampsia have produced conflicting results, and some evidence of harm has been reported.95, 96 The amount of lycopene in foods is assumed to be safe. Lycopene absorption in humans is approximately 10% to 30%, with the remaining excreted.1 The half-life elimination of lycopene in plasma was estimated to be 12 to 33 days, while a single-dose pharmacokinetic study documented 28 to 61 hours.85 The estimated daily dietary intake of the general population is 0.5 to 27 mg per person per day.86 Factors affecting uptake and absorption of carotenoids have been reported.87 Pharmacokinetic parameters of lycopene have been evaluated in humans.39, 88, 89, 90, 91, 92, 93, 94, Information regarding safety and efficacy in pregnancy and lactation is lacking. Lycopene is an antioxidant. Over 600 carotenoids have been identified in nature! Also related to its powerful antioxidative qualities, lycopene plays a role in … Find patient medical information for Lycopene Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. One clinical trial suggested that preventative use of lycopene supplements reduces the spread of localized prostate cancer, but there is no other proof from clinical trials that lycopene can treat cancer. Christopher Columbus may have learned of the nutritional benefits of fruits and tomatoes from the inhabitants of the New World.3 There is a large body of evidence documenting the health benefits of lycopene, as well as its biological activity in numerous human diseases.1, 2, 3, Lycopene is a 40-carbon acyclic carotenoid containing 11 conjugated double bonds, with a molecular mass of 536.2, 4, 5 It consists of only hydrogen and carbon atoms, and is 1 of 600 carotenoids synthesized by plants and photosynthetic microorganisms.2, 4 The biochemistry of lycopene is unique because it has no pro-vitamin A activity, unlike many other carotenoids, such as alpha-carotene and beta-carotene. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. Fast & Free shipping on many items! Participants received lycopene 7 mg or placebo daily for 2 months. Information regarding safety and efficacy in pregnancy and lactation is lacking. For years, scientists noted that diets high in beta-carotene FROM FOOD SOURCES, reduced risk of many types of cancer, including lung cancer in smokers. Gardian Capsules, Cipla The drug brand named Gardian Capsules contains generic salt-Choline and is manufactured by Cipla. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Scientific literature documents some GI complaints, such as diarrhea, dyspepsia, gas, nausea, and vomiting. Post-hoc analysis demonstrated a positive dose-response correlation between lycopene concentration and absolute change in EDV response between visits (P = 0.019). Non GMO by Jiva Botanicals, Jarrow Formulas Lyco-Sorb, Supports Prostate & Cardiovascular Health, 10 mg, 60 Softgels, 50mg Lycopene x 360 Tablets (2 Bottles of 180 Tablets Each - 12 Months Supply). “Cipla is a 83-year old start-up. Avoid use with hypersensitivity to lycopene or to any of its food sources, especially tomatoes. Meta-analysis revealed no difference in prostate-specific antigen levels or in lycopene levels with and without lycopene supplementation. Antimetastatic and anti-invasion activity. It is the most abundant carotenoid in tomatoes (0.9 to 4.2 mg per 100 g), followed by beta-carotene, gamma-carotene, phytoene, and other minor carotenoids,4 and is touted as the highest overall single oxygen-quenching carotenoid, with double the value of beta-carotene.6, Lycopene is relatively resistant to heat-induced geometrical isomerization in tomato processing.7 Processed tomato products are a better source of lycopene than fresh tomatoes,8 with lycopene more bioavailable.9 In addition, human uptake of lycopene is greater from heat-processed tomato juice than from unprocessed tomato juice.10 Tomato sauce and ketchup contain 33 to 68 mg of lycopene per 100 g, and raw tomatoes contain 3.1 mg of lycopene per 100 g.4, 6 Mechanical treatment with heat helps release lycopene from the tomato matrix, improving bioavailability, as seen with processed commercial tomato products versus fresh tomatoes. No association was found between lycopene levels and prostate cancer risk.35 However, a dose-response meta-analysis of 26 studies, 17,517 cases of prostate cancer and 563,299 participants, published through April 2014 identified a linear inverse relationship between lycopene intake and risk of prostate cancer with a dose threshold between 9 and 21 mg/day and an effective plasma concentration found not to exceed 85 mcg/L. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. Patients treated with the tomato extract also had reduced sputum neutrophil elastase activity.77 In a murine model of asthma, lycopene suppressed infiltration of inflammatory mediators and cells into the lung; decreased airway hyperresponsiveness; and inhibited cell infiltration and invasion.78 Lycopene may also have a role in reducing rhinovirus-induced airway inflammation by potentially inhibiting the formation of reactive oxygen species and decreasing viral replication.79. Last updated on Jan 20, 2020. There is no association between lycopene and the risk of bladder and colon cancers.. Promotes Heart Health Menopause and Bone Health Support. Herbs and supplements that might slow blood clotting Using herbs and supplements that slow blood clotting along with lycopene could increase the risk of bleeding in some people. Information about drug Lycopene combination includes cost of the drug and the type of drug - tablet, capsule, syrup, cream, gel, ointment, liquid or injection. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. The lycopene in supplements is about as easy for the body to use as lycopene found in food. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Like beta-carotene, lycopene is a carotenoid. In a review of epidemiologic studies, a diet rich in fresh tomatoes, tomato sauce, and pizza reduced the incidence of prostate cancer in a cohort of 40,000 men.19 Increased consumption of tomatoes statistically lowered the risk of prostate cancer in a cohort of 14,000 Seventh-day Adventist men.4, 28 A 2015 systematic review and dose-response meta-analysis of observational studies evaluating dietary intake (n = 13 studies) or blood concentrations (n = 15 studies) of lycopene on the risk of prostate cancer found a reduction in risk by 3% per 1 mg/day increment of dietary intake of lycopene. One trial documented a cancer-related hemorrhage in a patient taking lycopene, but causality was unclear.98 Tomato-based products are acidic and may irritate stomach ulcers. The powerful antioxidant properties of lycopene fight free radicals and oxidative stress. Some other herbs of this type include angelica, clove, danshen, garlic, ginger, Panax ginseng, and others. Lycopene is a powerful antioxidant, which means that, among nutrients, it has a greater-than-average ability to “quench” free radicals that cause damage to cells. Find here online price details of companies selling Lycopene Capsule. Lycopene is a common carotenoid compound found in fruits, vegetables, and green plants.1 It is responsible for a red plant pigment found primarily in tomatoes. Pooled data as well as subgroup analysis (ie, study design, smoking history, alcohol consumption, gender, geographical location) revealed no significant association between consumption of lycopene and the risk of colorectal cancer. Lycopene administered as a pure compound has been studied in clinical trials at dosages of Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. 50mg Lycopene x 360 Tablets (2 Bottles of 180 Tablets Each - 12 Months Supply). Lycogard Capsule may also be used for purposes not listed in this medication guide. Additionally, no dose relationship was observed.110. This is only a brief summary of general information about this product. Lycopene's efficient absorption from tomato products facilitates its antioxidant effects and may also play an important role in cancer prevention.36 Lycopene not only achieves high concentrations in the prostate, but also in the testes and adrenal glands. There's a problem loading this menu right now. Lycopene is part of the caratonoid group of substances. One cup of canned tomato paste provides 75 mg of lycopene, compared to 5 mg in one cup of raw tomatoes, the Linus Pauling Institute notes. Or placebo daily for 2 Months mg of lycopene fight free radicals and lycopene capsules cipla! Results are objective and unbiased to take this helpful carotinoid in the breast milk plasma. Diagnosis or treatment also protects your skin, thanks to its photoprotective properties its! 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